Differential gene expression profile in pig adipose tissue treated with/without clenbuterol.

ABSTRACT:

Background

Clenbuterol, a beta-agonist, can dramatically reduce pig adipose accumulation at high dosages. However, it has been banned in pig production because people who eat pig products treated with clenbuterol can be poisoned by the clenbuterol residues. To understand the molecular mechanism for this fat reduction, cDNA microarray, real-time PCR, two-dimensional electrophoresis and mass spectra were used to study the differential gene expression profiles of pig adipose tissues treated with/without clenbuterol. The objective of this research is to identify novel genes and physiological pathways that potentially facilitate clenbuterol induced reduction of adipose accumulation.

Results

Clenbuterol was found to improve the lean meat percentage about 10 percent (P < 0.05). The

SUBMITTER: Zhang J 

PROVIDER: S-EPMC2231380 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature