PiRNABank: a web resource on classified and clustered Piwi-interacting RNAs.

ABSTRACT: Piwi-interacting RNAs (piRNAs) are expressed in mammalian germline cells and have been identified as key players in germline development. These molecules, typically of length 25-33 nt, associate with Piwi proteins of the Argonaute family to form the Piwi-interacting RNA complex. These small regulatory RNAs have been implicated in spermatogenesis, repression of retrotransposon transposition in germline cells, epigenetic regulation and positive regulation of translation and mRNA stability. piRNABank is a highly user-friendly resource which stores empirically known sequences and other related information on piRNAs reported in human, mouse and rat. The database supports organism and chromosome-wise comprehensive search features including accession numbers, localization on chromosomes, gene nam

SUBMITTER: Sai Lakshmi S 

PROVIDER: S-EPMC2238943 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature