Effects of continuous versus cyclical oral contraception: a randomized controlled trial.

ABSTRACT:

Context

Continuous oral contraception may better suppress the ovary and endometrium, lending itself to the treatment of other medical conditions.

Objective

Our objective was to determine the effects of continuous vs. cyclical oral contraception.

Design

This was a randomized double-blind trial.

Setting

This trial was performed at an academic medical center in Pennsylvania.

Patients

A total of 62 healthy women with regular menses were included in the study.

Intervention

Cyclical oral contraception (21-d active/7-d placebo given for six consecutive 28-d cycles) vs. continuous (168-d active pill) therapy using a monophasic pill (20 microg ethinyl estradiol and 1 mg norethindrone acetate) was examined.

Main outcome measures

The primary outcome w

SUBMITTER: Legro RS 

PROVIDER: S-EPMC2243231 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature