Diversity arrays technology (DArT) for pan-genomic evolutionary studies of non-model organisms.

ABSTRACT:

Background

High-throughput tools for pan-genomic study, especially the DNA microarray platform, have sparked a remarkable increase in data production and enabled a shift in the scale at which biological investigation is possible. The use of microarrays to examine evolutionary relationships and processes, however, is predominantly restricted to model or near-model organisms.

Methodology/principal findings

This study explores the utility of Diversity Arrays Technology (DArT) in evolutionary studies of non-model organisms. DArT is a hybridization-based genotyping method that uses microarray technology to identify and type DNA polymorphism. Theoretically applicable to any organism (even one for which no prior genetic data are available), DArT has not yet been explored in exclusi

SUBMITTER: James KE 

PROVIDER: S-EPMC2244804 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature