Predicting the interactome of Xanthomonas oryzae pathovar oryzae for target selection and DB service.

ABSTRACT:

Background

Protein-protein interactions (PPIs) play key roles in various cellular functions. In addition, some critical inter-species interactions such as host-pathogen interactions and pathogenicity occur through PPIs. Phytopathogenic bacteria infect hosts through attachment to host tissue, enzyme secretion, exopolysaccharides production, toxins release, iron acquisition, and effector proteins secretion. Many such mechanisms involve some kind of protein-protein interaction in hosts. Our first aim was to predict the whole protein interaction pairs (interactome) of Xanthomonas oryzae pathovar oryzae (Xoo) that is an important pathogenic bacterium that causes bacterial blight (BB) in rice. We developed a detection protocol to find possibly interacting proteins in its host using whole

SUBMITTER: Kim JG 

PROVIDER: S-EPMC2246157 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature