Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors.

ABSTRACT:

Background

The Potato type II (Pot II) family of proteinase inhibitors plays critical roles in the defense system of plants from Solanaceae family against pests. To better understand the evolution of this family, we investigated the correlation between sequence and structural repeats within this family and the evolution and molecular adaptation of Pot II genes through computational analysis, using the putative ancestral domain sequence as the basic repeat unit.

Results

Our analysis discovered the following interesting findings in Pot II family. (1) We classified the structural domains in Pot II family into three types (original repeat domain, circularly permuted domain, the two-chain domain) according to the existence of two linkers between the two domain components, which c

SUBMITTER: Kong L 

PROVIDER: S-EPMC2259423 | biostudies-literature | 2008

REPOSITORIES: biostudies-literature