A process for analysis of microarray comparative genomics hybridisation studies for bacterial genomes.

ABSTRACT:

Background

Microarray based comparative genomic hybridisation (CGH) experiments have been used to study numerous biological problems including understanding genome plasticity in pathogenic bacteria. Typically such experiments produce large data sets that are difficult for biologists to handle. Although there are some programmes available for interpretation of bacterial transcriptomics data and CGH microarray data for looking at genetic stability in oncogenes, there are none specifically to understand the mosaic nature of bacterial genomes. Consequently a bottle neck still persists in accurate processing and mathematical analysis of these data. To address this shortfall we have produced a simple and robust CGH microarray data analysis process that may be automated in the future to u

SUBMITTER: Carter B 

PROVIDER: S-EPMC2262894 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature