Effect of Lactobacillus acidophilus supernatants on body weight and leptin expression in rats.

ABSTRACT:

Background

Lactobacillus extracts and supernatants have been used as probiotics in human and veterinary medicine for their ability to enhance wound healing and immunity. Previous data from our laboratory demonstrated that Lactobacillus supernatant (LS) stimulated wound healing, angiogenesis and proliferation of embryonic cells after topical application. This current study shows that LS after its administration into the cerebral ventricles of male rats exerts systemic effects.

Methods

The right lateral cerebral ventricle of young male rats was accessed through intracerebroventricular cannulation (ICV) under anesthesia and aseptic conditions. One group of control rats received saline solution, a second control group received 0.8 M lactic acid solution (to control for acidity o

SUBMITTER: Sousa R 

PROVIDER: S-EPMC2263016 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature