Duplicate gene evolution and expression in the wake of vertebrate allopolyploidization.

ABSTRACT:

Background

The mechanism by which duplicate genes originate - whether by duplication of a whole genome or of a genomic segment - influences their genetic fates. To study events that trigger duplicate gene persistence after whole genome duplication in vertebrates, we have analyzed molecular evolution and expression of hundreds of persistent duplicate gene pairs in allopolyploid clawed frogs (Xenopus and Silurana). We collected comparative data that allowed us to tease apart the molecular events that occurred soon after duplication from those that occurred later on. We also quantified expression profile divergence of hundreds of paralogs during development and in different tissues.

Results

Our analyses indicate that persistent duplicates generated by allopolyploidization are s

SUBMITTER: Chain FJ 

PROVIDER: S-EPMC2275784 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature