Insulin resistance, hyperinsulinemia, and energy intake in overweight children.

ABSTRACT:

Objective

To examine the relationship between energy intake during a buffet meal and indexes of insulin dynamics in overweight children.

Study design

Ninety-five nondiabetic, overweight (body mass index > or = 95th percentile) children (age 10.3 +/- 1.4 years) selected lunch from a 9835-kcal buffet eaten ad libitum after an overnight fast. The associations between energy intake and measures of insulin dynamics, in the postabsorptive state and during a 2-hour hyperglycemic clamp, were determined. Covariates in the statistical model included race, sex, skeletal age, fat-free mass, fat mass, socioeconomic status, and number of foods in the buffet rated as acceptable.

Results

Energy intake was positively associated with the fasting homeostasis model assessment for insulin

SUBMITTER: Han JC 

PROVIDER: S-EPMC2276579 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature