Expression of the Ladybird-like homeobox 2 transcription factor in the developing mouse testis and epididymis.

ABSTRACT:

Background

Homeoproteins are a class of transcription factors that are well-known regulators of organogenesis and cell differentiation in numerous tissues, including the male reproductive system. Indeed, a handful of homeoproteins have so far been identified in the testis and epididymis where a few were shown to play important developmental roles. Through a degenerate PCR approach aimed at identifying novel homeoproteins expressed in the male reproductive system, we have detected several homeoproteins most of which had never been described before in this tissue. One of these homeoproteins is Ladybird-like homeobox 2 (Lbx2), a homeobox factor mostly known to be expressed in the nervous system.

Results

To better define the expression profile of Lbx2 in the male reproductive sy

SUBMITTER: Moisan V 

PROVIDER: S-EPMC2277406 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature