Multilocus patterns of polymorphism and selection across the X chromosome of Caenorhabditis remanei.

ABSTRACT: Natural selection and neutral processes such as demography, mutation, and gene conversion all contribute to patterns of polymorphism within genomes. Identifying the relative importance of these varied components in evolution provides the principal challenge for population genetics. To address this issue in the nematode Caenorhabditis remanei, I sampled nucleotide polymorphism at 40 loci across the X chromosome. The site-frequency spectrum for these loci provides no evidence for population size change, and one locus presents a candidate for linkage to a target of balancing selection. Selection for codon usage bias leads to the non-neutrality of synonymous sites, and despite its weak magnitude of effect (N(e)s approximately 0.1), is responsible for profound patterns of diversity and divergen

SUBMITTER: Cutter AD 

PROVIDER: S-EPMC2278095 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature