Ontology highlight
ABSTRACT:
SUBMITTER: Vardy E
PROVIDER: S-EPMC2279927 | biostudies-literature | 2004 Jul
REPOSITORIES: biostudies-literature
Vardy Eyal E Arkin Isaiah T IT Gottschalk Kay E KE Kaback H Ronald HR Schuldiner Shimon S
Protein science : a publication of the Protein Society 20040701 7
The structures of membrane transporters are still mostly unsolved. Only recently, the first two high-resolution structures of transporters of the major facilitator superfamily (MFS) were published. Despite the low sequence similarity of the two proteins involved, lactose permease and glycerol-3-phosphate transporter, the reported structures are highly similar. This leads to the hypothesis that all members of the MFS share a similar structure, regardless of their low sequence identity. To test th ...[more]