Up-regulation of multiple proteins and biological processes during maxillary expansion in rats.

ABSTRACT:

Background

Maxillary expansion (ME) is a common practice in orthodontics that aims to increase the constricted maxillary arch width. Relapse often occurs, however, and better treatment strategies are needed. In order to develop a more effective method, this study was designed to further examine the process of tissue remodeling during ME, to identify the changes in expression of several proteins of interest, and to clarify the molecular mechanism responsible for tissue remodeling.

Methods

Male Wistar rats were randomly divided into control and ME groups. The rats were euthanized at various intervals over 11 days, and the dissected palates were prepared for histological examination. The structure of the midpalatal sutures changed little during the first three days. Proteins fr

SUBMITTER: Ma J 

PROVIDER: S-EPMC2291465 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature