Encoding problem-solving strategies in prefrontal cortex: activity during strategic errors.

ABSTRACT: The primate prefrontal cortex (PF) plays a central role in choosing goals and strategies. To better understand its mechanisms, we recorded from PF neurons as monkeys used abstract response strategies to select a spatial goal. A visual cue, selected randomly from a set of three cues, appeared on each trial. All three cues were novel when neuronal recording commenced. From trial to trial, the cue could have either been repeated or changed from the previous trial; these were called repeat trials and change trials, respectively. On repeat trials, the monkeys used a Repeat-stay strategy to gain a reward by choosing the same spatial goal as on the previous trial; on change trials, they used a Change-shift strategy to reject the previous goal in favour of an alternative. We reported previously th

SUBMITTER: Genovesio A 

PROVIDER: S-EPMC2292125 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature