Aspergillus calidoustus sp. nov., causative agent of human infections previously assigned to Aspergillus ustus.

ABSTRACT: Aspergillus ustus is a relatively rare human pathogen causing invasive infections in immunocompromised hosts. In this study isolates originating from clinical and other sources have been examined using molecular, morphological, and physiological approaches to clarify their species assignment. Phylogenetic analysis of partial beta-tubulin, calmodulin, actin, and intergenic transcribed spacer sequences indicated that none of the clinical isolates recognized previously as A. ustus belongs to this species. All but two of these isolates formed a well-defined clade related to A. pseudodeflectus based on sequence analysis of protein-coding regions. Morphological and physiological examination of these isolates indicated that they are able to grow above 37 degrees C, in contrast with A. ustus isola

SUBMITTER: Varga J 

PROVIDER: S-EPMC2292628 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature