Effect of mechanical ventilation in the prone position on clinical outcomes in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis.

ABSTRACT:

Background

Mechanical ventilation in the prone position is used to improve oxygenation in patients with acute hypoxemic respiratory failure. We sought to determine the effect of mechanical ventilation in the prone position on mortality, oxygenation, duration of ventilation and adverse events in patients with acute hypoxemic respiratory failure.

Methods

In this systematic review we searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and Science Citation Index Expanded for articles published from database inception to February 2008. We also conducted extensive manual searches and contacted experts. We extracted physiologic data and clinically relevant outcomes.

Results

Thirteen trials that enrolled a total of 1559 patients met our inclusion crit

SUBMITTER: Sud S 

PROVIDER: S-EPMC2292779 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature