Determination of molecular phylogenetics of Vibrio parahaemolyticus strains by multilocus sequence typing.

ABSTRACT: Vibrio parahaemolyticus is an important human pathogen whose transmission is associated with the consumption of contaminated seafood. There is a growing public health concern due to the emergence of a pandemic strain causing severe outbreaks worldwide. Many questions remain unanswered regarding the evolution and population structure of V. parahaemolyticus. In this work, we describe a multilocus sequence typing (MLST) scheme for V. parahaemolyticus based on the internal fragment sequences of seven housekeeping genes. This MLST scheme was applied to 100 V. parahaemolyticus strains isolated from geographically diverse clinical (n = 37) and environmental (n = 63) sources. The sequences obtained from this work were deposited and are available in a public database (http://pubmlst.org/vparahaemol

SUBMITTER: Gonzalez-Escalona N 

PROVIDER: S-EPMC2293261 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature