Sequence variability of Campylobacter temperate bacteriophages.

ABSTRACT:

Background

Prophages integrated within the chromosomes of Campylobacter jejuni isolates have been demonstrated very recently. Prior work with Campylobacter temperate bacteriophages, as well as evidence from prophages in other enteric bacteria, suggests these prophages might have a role in the biology and virulence of the organism. However, very little is known about the genetic variability of Campylobacter prophages which, if present, could lead to differential phenotypes in isolates carrying the phages versus those that do not. As a first step in the characterization of C. jejuni prophages, we investigated the distribution of prophage DNA within a C. jejuni population assessed the DNA and protein sequence variability within a subset of the putative prophages found.

Results

SUBMITTER: Clark CG 

PROVIDER: S-EPMC2323383 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature