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An anatomy ontology to represent biological knowledge in Dictyostelium discoideum.


ABSTRACT:

Background

Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information.

Results

We present here an anatomy ontology for Dictyostelium based upon the life cycle of the organism.

Conclusion

Anatomy ontologies are necessary to annotate species-specific events such as phenotypes, and the Dictyostelium anatomy ontology provides an essential tool for curation of the Dictyostelium genome.

SUBMITTER: Gaudet P 

PROVIDER: S-EPMC2323390 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature

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Publications

An anatomy ontology to represent biological knowledge in Dictyostelium discoideum.

Gaudet Pascale P   Williams Jeffery G JG   Fey Petra P   Chisholm Rex L RL  

BMC genomics 20080318


<h4>Background</h4>Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information.<h4>Results</h4>We present here an anatomy ontology for Dictyostelium based upon the life cycle of the o  ...[more]

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