Gene expression analysis of the ovary of hybrid females of Xenopus laevis and X. muelleri.

ABSTRACT:

Background

Interspecific hybrids of frogs of the genus Xenopus result in sterile hybrid males and fertile hybrid females. Previous work has demonstrated a dramatic asymmetrical pattern of misexpression in hybrid males compared to the two parental species with relatively few genes misexpressed in comparisons of hybrids and the maternal species (X. laevis) and dramatically more genes misexpressed in hybrids compared to the paternal species (X. muelleri). In this work, we examine the gene expression pattern in hybrid females of X. laevis x X. muelleri to determine if this asymmetrical pattern of expression also occurs in hybrid females.

Results

We find a similar pattern of asymmetry in expression compared to males in that there were more genes differentially expressed between h

SUBMITTER: Malone JH 

PROVIDER: S-EPMC2330042 | biostudies-literature | 2008 Mar

REPOSITORIES: biostudies-literature