Protein targeting to ATP-dependent proteases.

ABSTRACT: ATP-dependent proteases control diverse cellular processes by degrading specific regulatory proteins. Recent work has shown that protein substrates are specifically transferred to ATP-dependent proteases through different routes. These routes can function in parallel or independently. In all of these targeting mechanisms, it can be useful to separate two steps: substrate binding to the protease and initiation of degradation.

SUBMITTER: Inobe T 

PROVIDER: S-EPMC2346608 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature