Application of an intramolecular dipolar cycloaddition to an asymmetric synthesis of the fully oxygenated tricyclic core of the stemofoline alkaloids.

ABSTRACT: An intramolecular non-stabilized azomethine ylide dipolar cycloaddition was applied toward the first non-racemic synthesis of the fully-oxygenated bridged pyrrolizidine core (45) of (+)-stemofoline (1) in eleven steps from a commercially available starting material.

SUBMITTER: Carra RJ 

PROVIDER: S-EPMC2352155 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature