Ontology highlight
ABSTRACT:
SUBMITTER: Joiner WJ
PROVIDER: S-EPMC23566 | biostudies-literature | 1997 Sep
REPOSITORIES: biostudies-literature
Joiner W J WJ Wang L Y LY Tang M D MD Kaczmarek L K LK
Proceedings of the National Academy of Sciences of the United States of America 19970901 20
The gene for hSK4, a novel human small conductance calcium-activated potassium channel, or SK channel, has been identified and expressed in Chinese hamster ovary cells. In physiological saline hSK4 generates a conductance of approximately 12 pS, a value in close agreement with that of other cloned SK channels. Like other members of this family, the polypeptide encoded by hSK4 contains a previously unnoted leucine zipper-like domain in its C terminus of unknown function. hSK4 appears unique, howe ...[more]