A new classification system for bacterial Rieske non-heme iron aromatic ring-hydroxylating oxygenases.

ABSTRACT:

Background

Rieske non-heme iron aromatic ring-hydroxylating oxygenases (RHOs) are multi-component enzyme systems that are remarkably diverse in bacteria isolated from diverse habitats. Since the first classification in 1990, there has been a need to devise a new classification scheme for these enzymes because many RHOs have been discovered, which do not belong to any group in the previous classification. Here, we present a scheme for classification of RHOs reflecting new sequence information and interactions between RHO enzyme components.

Result

We have analyzed a total of 130 RHO enzymes in which 25 well-characterized RHO enzymes were used as standards to test our hypothesis for the proposed classification system. From the sequence analysis of electron transport chain (ETC)

SUBMITTER: Kweon O 

PROVIDER: S-EPMC2358900 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature