In silico identification of conserved microRNAs in large number of diverse plant species.

ABSTRACT:

Background

MicroRNAs (miRNAs) are recently discovered small non-coding RNAs that play pivotal roles in gene expression, specifically at the post-transcriptional level in plants and animals. Identification of miRNAs in large number of diverse plant species is important to understand the evolution of miRNAs and miRNA-targeted gene regulations. Now-a-days, publicly available databases play a central role in the in-silico biology. Because, at least ~21 miRNA families are conserved in higher plants, a homology based search using these databases can help identify orthologs or paralogs in plants.

Results

We searched all publicly available nucleotide databases of genome survey sequences (GSS), high-throughput genomics sequences (HTGS), expressed sequenced tags (ESTs) and nonredundan

SUBMITTER: Sunkar R 

PROVIDER: S-EPMC2358906 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature