PSAIA - protein structure and interaction analyzer.

ABSTRACT:

Background

PSAIA (Protein Structure and Interaction Analyzer) was developed to compute geometric parameters for large sets of protein structures in order to predict and investigate protein-protein interaction sites.

Results

In addition to most relevant established algorithms, PSAIA offers a new method PIADA (Protein Interaction Atom Distance Algorithm) for the determination of residue interaction pairs. We found that PIADA produced more satisfactory results than comparable algorithms implemented in PSAIA. Particular advantages of PSAIA include its capacity to combine different methods to detect the locations and types of interactions between residues and its ability, without any further automation steps, to handle large numbers of protein structures and complexes. Generally,

SUBMITTER: Mihel J 

PROVIDER: S-EPMC2364630 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature