A noncanonical WD-repeat protein from the cyanobacterium Synechocystis PCC6803: structural and functional study.

ABSTRACT: SYNECHOCYSTIS: PCC6803 possesses several open reading frames encoding putative WD-repeat proteins. One, the Hat protein, is involved in the control of a high-affinity transport system for inorganic carbon that is active when the cells are grown under a limiting concentration of this carbon substrate. The protein is composed of two major domains separated by a hydrophobic linker region of 20 amino acid residues. The N-terminal domain of Hat has no homolog in standard databases and does not display any particular structural features. Eleven WD repeats have been identified in the C-terminal moiety. The region encompassing the four terminal WD repeats is essential for growth under a limiting inorganic carbon regime. The region encompassing the two most terminal WD repeats is required for the a

SUBMITTER: Hisbergues M 

PROVIDER: S-EPMC2373943 | biostudies-literature | 2001 Feb

REPOSITORIES: biostudies-literature