RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes.
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ABSTRACT:
SUBMITTER: Sevin EW
PROVIDER: S-EPMC2374986 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Publications
RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes.
Sevin Emeric W EW Barloy-Hubler Frédérique F
Genome biology 20070101 8
Toxin/antitoxin (TA) systems, viewed as essential regulators of growth arrest and programmed cell death, are widespread among prokaryotes, but remain sparsely annotated. We present RASTA-Bacteria, an automated method allowing quick and reliable identification of TA loci in sequenced prokaryotic genomes, whether they are annotated open reading frames or not. The tool successfully confirmed all reported TA systems, and spotted new putative loci upon screening of sequenced genomes. RASTA-Bacteria i ...[more]
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