MPDA: microarray pooled DNA analyzer.

ABSTRACT:

Background

Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new technique uses pooled DNA, thereby reducing costs associated with the typing of DNA from numerous individuals. Moreover, use of an oligonucleotide gene chip reduces costs related to processing various DNA segments (e.g., primers, reagents). Thus, the technique provides an overall cost-effective solution for large-scale genomic/genetic research. However, few publicly shared tools are available to systematically analyze the rapidly accumulating volume of whole-genome pooled DNA data.

Results

We propose a generalized concept of pooled DNA and present a user-friendly tool named Microarray Pooled DNA Analyzer (M

SUBMITTER: Yang HC 

PROVIDER: S-EPMC2387178 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature