Gene expression profiling of flagellar disassembly in Chlamydomonas reinhardtii.

ABSTRACT: Flagella are sensory organelles that interact with the environment through signal transduction and gene expression networks. We used microarray profiling to examine gene regulation associated with flagellar length change in the green alga Chlamydomonas reinhardtii. Microarrays were probed with fluorescently labeled cDNAs synthesized from RNA extracted from cells before and during flagellar assembly or disassembly. Evaluation of the gene expression profiles identified >100 clones showing at least a twofold change in expression during flagellar length changes. Products of these genes are associated not only with flagellar structure and motility but also with other cellular responses, including signal transduction and metabolism. Expression of specific genes from each category was further cha

SUBMITTER: Chamberlain KL 

PROVIDER: S-EPMC2390646 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature