Airway wall thickness assessed using computed tomography and optical coherence tomography.

ABSTRACT:

Rationale

Computed tomography (CT) has been shown to reliably measure the airway wall dimensions of medium to large airways. Optical coherence tomography (OCT) is a promising new micron-scale resolution imaging technique that can image small airways 2 mm in diameter or less.

Objectives

To correlate OCT measurements of airway dimensions with measurements assessed using CT scans and lung function.

Methods

Forty-four current and former smokers received spirometry, CT scans, and OCT imaging at the time of bronchoscopy. Specific bronchial segments were identified and measured using the OCT images and three-dimensional reconstructions of the bronchial tree using CT.

Measurements and main results

There was a strong correlation between CT and OCT measurements of lumen

SUBMITTER: Coxson HO 

PROVIDER: S-EPMC2408438 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature