Short-term variations in response distribution to cortical stimulation.

ABSTRACT: Patterns of responses in the cerebral cortex can vary, and are influenced by pre-existing cortical function, but it is not known how rapidly these variations can occur in humans. We investigated how rapidly response patterns to electrical stimulation can vary in intact human brain. We also investigated whether the type of functional change occurring at a given location with stimulation would help predict the distribution of responses elsewhere over the cortex to stimulation at that given location. We did this by studying cortical afterdischarges following electrical stimulation of the cortex in awake humans undergoing evaluations for brain surgery. Response occurrence and location could change within seconds, both nearby to and distant from stimulation sites. Responses might occur at a giv

SUBMITTER: Lesser RP 

PROVIDER: S-EPMC2408939 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature