A polyadenylation factor subunit implicated in regulating oxidative signaling in Arabidopsis thaliana.

ABSTRACT:

Background

Plants respond to many unfavorable environmental conditions via signaling mediated by altered levels of various reactive oxygen species (ROS). To gain additional insight into oxidative signaling responses, Arabidopsis mutants that exhibited tolerance to oxidative stress were isolated. We describe herein the isolation and characterization of one such mutant, oxt6.

Methodology/principal findings

The oxt6 mutation is due to the disruption of a complex gene (At1g30460) that encodes the Arabidopsis ortholog of the 30-kD subunit of the cleavage and polyadenylation specificity factor (CPSF30) as well as a larger, related 65-kD protein. Expression of mRNAs encoding Arabidopsis CPSF30 alone was able to restore wild-type growth and stress susceptibility to the oxt6 mutant.

SUBMITTER: Zhang J 

PROVIDER: S-EPMC2408970 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature