Genetic and epigenetic analyses of MBD3 in colon and lung cancer.

ABSTRACT: MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC2410281 | biostudies-literature | 2004 May

REPOSITORIES: biostudies-literature