Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC2424238 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Zhang Haitao H Dong Yan Y Zhao Hongjuan H Brooks James D JD Hawthorn Lesleyann L Nowak Norma N Marshall James R JR Gao Allen C AC Ip Clement C
Cancer genomics & proteomics 20050401 2
BACKGROUND: A previous clinical trial showed that selenium supplementation significantly reduced the incidence of prostate cancer. We report here a bioinformatics approach to gain new insights into selenium molecular targets that might be relevant to prostate cancer chemoprevention. MATERIALS AND METHODS: We first performed data mining analysis to identify genes which are consistently dysregulated in prostate cancer using published datasets from gene expression profiling of clinical prostate spe ...[more]