Recurrent events of positive selection in independent Drosophila lineages at the spermatogenesis gene roughex.

ABSTRACT: Our understanding of the role of positive selection in the evolution of genes with male-biased expression can be hindered by two observations. First, male-biased genes tend to be overrepresented among lineage-specific genes. Second, novel genes are prone to experience bursts of adaptive evolution shortly after their formation. A thorough study of the forces acting on male-biased genes therefore would benefit from phylogenywide analyses that could distinguish evolutionary trends associated with gene formation and later events, while at the same time tackling the interesting question of whether adaptive evolution is indeed idiosyncratic. Here we investigate the roughex (rux) gene, a dose-dependent regulator of Drosophila spermatogenesis with a C-terminal domain responsible for nuclear locali

SUBMITTER: Llopart A 

PROVIDER: S-EPMC2429854 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature