Cardiac damage after treatment of childhood cancer: a long-term follow-up.

ABSTRACT:

Background

With improved childhood cancer cure rate, long term sequelae are becoming an important factor of quality of life. Signs of cardiovascular disease are frequently found in long term survivors of cancer. Cardiac damage may be related to irradiation and chemotherapy.We have evaluated simultaneous influence of a series of independent variables on the late cardiac damage in childhood cancer survivors in Slovenia and identified groups at the highest risk.

Methods

211 long-term survivors of different childhood cancers, at least five years after treatment were included in the study. The evaluation included history, physical examination, electrocardiograpy, exercise testing and echocardiograpy. For analysis of risk factors, beside univariate analysis, multivariate classific

SUBMITTER: Velensek V 

PROVIDER: S-EPMC2430718 | biostudies-literature | 2008 May

REPOSITORIES: biostudies-literature