Maintenance metabolism and carbon fluxes in Bacillus species.

ABSTRACT:

Background

Selection of an appropriate host organism is crucial for the economic success of biotechnological processes. A generally important selection criterion is a low maintenance energy metabolism to reduce non-productive consumption of substrate. We here investigated, whether various bacilli that are closely related to Bacillus subtilis are potential riboflavin production hosts with low maintenance metabolism.

Results

While B. subtilis exhibited indeed the highest maintenance energy coefficient, B. licheniformis and B. amyloliquefaciens exhibited only statistically insignificantly reduced maintenance metabolism. Both B. pumilus and B. subtilis (natto) exhibited irregular growth patterns under glucose limitation such that the maintenance metabolism could not be determine

SUBMITTER: Tannler S 

PROVIDER: S-EPMC2442585 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature