Male-biased genes are overrepresented among novel Drosophila pseudoobscura sex-biased genes.

ABSTRACT:

Background

The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often involved in male reproduction.

Results

With the aim of identifying novel genes, we used the technique "generation of longer cDNA fragments from serial analysis of gene expression (SAGE) tags for gene identification (GLGI)" to extend 84 sex-biased 3'end SAGE tags that previously could not be mapped to the D. pseudoobscura transcriptome. Eleven male-biased and 33 female-biased GLGI fragments were obtained, of which 5 male-biased and 3 female-biased tags corresponded to putatively novel genes. This excess of novel genes with a male-biased gene expression pattern is consistent with pre

SUBMITTER: Metta M 

PROVIDER: S-EPMC2443716 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature