The genetic architecture of susceptibility to parasites.

ABSTRACT:

Background

The antagonistic co-evolution of hosts and their parasites is considered to be a potential driving force in maintaining host genetic variation including sexual reproduction and recombination. The examination of this hypothesis calls for information about the genetic basis of host-parasite interactions - such as how many genes are involved, how big an effect these genes have and whether there is epistasis between loci. We here examine the genetic architecture of quantitative resistance in animal and plant hosts by concatenating published studies that have identified quantitative trait loci (QTL) for host resistance in animals and plants.

Results

Collectively, these studies show that host resistance is affected by few loci. We particularly show that additional epist

SUBMITTER: Wilfert L 

PROVIDER: S-EPMC2446395 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature