Population structure of the fish-pathogenic bacterium Flavobacterium psychrophilum.

ABSTRACT: Flavobacterium psychrophilum is currently one of the main bacterial pathogens hampering the productivity of salmonid farming worldwide, and its control mainly relies on antibiotic treatments. To better understand the population structure of this bacterium and its mode of evolution, we have examined the nucleotide polymorphisms at 11 protein-coding loci of the core genome in a set of 50 isolates. These isolates were selected to represent the broadest possible diversity, originating from 10 different host fish species and four continents. The nucleotide diversity between pairs of sequences amounted to fewer than four differences per kilobase on average, corresponding to a particularly low level of diversity, possibly indicative of a small effective-population size. The recombination rate, ho

SUBMITTER: Nicolas P 

PROVIDER: S-EPMC2446562 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature