Development and characterization of an equine infectious anemia virus Env-pseudotyped reporter virus.

ABSTRACT: We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV Env-pseudotyped virus were similar to those of replication-competent virus. An EIAV Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.

SUBMITTER: Tallmadge RL 

PROVIDER: S-EPMC2446648 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature