Dietary patterns, insulin resistance, and incidence of type 2 diabetes in the Whitehall II Study.

ABSTRACT:

Objective

The aim of this study was to identify a dietary pattern associated with insulin resistance and investigate whether this pattern was prospectively associated with type 2 diabetes.

Research design and methods

Analysis was based on 7,339 participants of the Whitehall II study. Dietary intake was measured using a 127-item food frequency questionnaire. We used the reduced rank regression method to determine dietary patterns using the homeostasis model assessment of insulin resistance as the intermediate or response variable. The association between the dietary pattern identified and incidence of type 2 diabetes was investigated using Cox proportional hazard regression models.

Results

We identified a dietary pattern characterized by high consumption of low-calorie

SUBMITTER: McNaughton SA 

PROVIDER: S-EPMC2453656 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature