Adipose tissue lipolysis is upregulated in lean and obese men during acute resistance exercise.

ABSTRACT:

Objective

To investigate the effect of acute resistance exercise on adipose tissue triacylglycerol lipase activity (TGLA) in lean and obese men.

Research design and methods

Nine lean and eight obese men performed 30 min of circuit resistance exercise. Adipose tissue and blood were sampled during exercise for TGLA, metabolite, and hormone determinations. Respiratory exchange ratio (RER) was measured throughout exercise.

Results

Energy expenditure of exercise relative to body mass was higher in the lean and RER was higher in the obese men, suggesting lower fat oxidation. TGLA increased 18-fold at 5 min of exercise in the lean men and 16-fold at 10 min of exercise in the obese men. The delayed lipolytic activation in the obese men was reflected in serum nonesterified fat

SUBMITTER: Chatzinikolaou A 

PROVIDER: S-EPMC2453678 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature