On the nature of fur evolution: a phylogenetic approach in Actinobacteria.

ABSTRACT:

Background

An understanding of the evolution of global transcription regulators is essential for comprehending the complex networks of cellular metabolism that have developed among related organisms. The fur gene encodes one of those regulators - the ferric uptake regulator Fur - widely distributed among bacteria and known to regulate different genes committed to varied metabolic pathways. On the other hand, members of the Actinobacteria comprise an ecologically diverse group of bacteria able to inhabit various natural environments, and for which relatively little is currently understood concerning transcriptional regulation.

Results

BLAST analyses revealed the presence of more than one fur homologue in most members of the Actinobacteria whose genomes have been fully sequenc

SUBMITTER: Santos CL 

PROVIDER: S-EPMC2464607 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature