Randomized trial of peribulbar triamcinolone acetonide with and without focal photocoagulation for mild diabetic macular edema: a pilot study.

ABSTRACT:

Objective

To provide pilot data on the safety and efficacy of anterior and posterior sub-Tenon injections of triamcinolone either alone or in combination with focal photocoagulation in the treatment of mild diabetic macular edema (DME).

Design

Prospective, phase II, multicenter, randomized clinical trial.

Participants

One hundred nine patients (129 eyes) with mild DME and visual acuity 20/40 or better.

Methods

The participants were assigned randomly to receive either focal photocoagulation (n = 38), a 20-mg anterior sub-Tenon injection of triamcinolone (n = 23), a 20-mg anterior sub-Tenon injection followed by focal photocoagulation after 4 weeks (n = 25), a 40-mg posterior sub-Tenon injection of triamcinolone (n = 21), or a 40-mg posterior sub-Tenon injection

SUBMITTER: Diabetic Retinopathy Clinical Research Network 

PROVIDER: S-EPMC2465806 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature