Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors.

ABSTRACT: Translation inhibitors of the 3,5-diamino-piperidine series act as aminoglycoside mimetics that inhibit bacterial growth. Here we show antibacterial SAR in the presence and absence of serum with a particular focus toward Pseudomonas aeruginosa.

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC2474707 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature