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ABSTRACT: Background
Virus infection induces the activation and suppression of global gene expression in the host. Profiling gene expression changes in the host may provide insights into the molecular mechanisms that underlie host physiological and phenotypic responses to virus infection. In this study, the Arabidopsis Affymetrix ATH1 array was used to assess global gene expression changes in Arabidopsis thaliana plants infected with Plum pox virus (PPV). To identify early genes in response to PPV infection, an Arabidopsis synchronized single-cell transformation system was developed. Arabidopsis protoplasts were transfected with a PPV infectious clone and global gene expression changes in the transfected protoplasts were profiled.Results
Microarray analysis of PPV-infected Arabidopsi
SUBMITTER: Babu M
PROVIDER: S-EPMC2478689 | biostudies-literature | 2008 Jul
REPOSITORIES: biostudies-literature