Ontology highlight
ABSTRACT:
SUBMITTER: Srichai MB
PROVIDER: S-EPMC2488270 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Journal of the American Society of Nephrology : JASN 20080521 8
Ischemia- or toxin-induced acute kidney injury is generally thought to affect the cells of the proximal tubule, but it has been difficult to define the involvement of other tubular segments because of the widespread damage caused by ischemia/reperfusion or toxin-induced injury in experimental models. For evaluation of whether thick ascending limb (TAL)-specific epithelial injury results in acute kidney injury, a novel transgenic mouse model that expresses the herpes simplex virus 1 thymidine kin ...[more]